The following is a list of historically significant college football games. Games included on this list are single college football games that have historical impact to the sport of college football.
Inclusion on this list requires games of significant historical "firsts" and/or otherwise significant impact to the sport itself, such as significant rules changes or initiation of long-standing ceremony. Historically significant games should be prominently discussed in major historical accounts of college football. Games that may be significant only to a particular team's fan base should not be listed here.
Games are listed in chronological order. The name of the winning team is in bold.
See also
- History of American football
- Category:American football incidents
- Category:College football games
- Game of the Century (college football)
- AP Poll#No. 1 vs. No. 2
- List of NCAA college football rivalry games
- List of college bowl games
- College football on television
- College Football Hall of Fame
- List of NCAA football records
- Bowl Championship Series
- List of NCAA conferences
- List of college athletic conferences in the United States
- List of the first college football game in each US state